1. What was the primary disease in this movie and whom did it affect?
Lorenzo Adone was affected with the disease Adrenoleukodystrophy (ALD).
2. How would you classify the disease' impact on the patients functional status..mild, moderate or severe, and
why?
I would classify the patients fundamental status as severe. When he was first diagnosed he had mild symptoms.
Then shortly after, he started loosing his sight, vision, hearing, movement, and then he died.
3. In your opinion, how did the research doctors regard Lorenzo's parents?
Some researchers were willing to help his parents to an extent. They wanted to have everything thoroughly tested
before anything was said, which could have taken several months or years. They also found his parents to be very pushy
at times. Very few researchers, like the one in the end, were willing to help them out.
4. "The roles of the researchers were juxtaposed or changed in this movie." Explain why this is true.
Lorenzo's parents conducted their own research on ALD. In order for them to understand what was going on they had
to gather all of the research. His parents were explaining information to the doctors.
5. Dad had a breakthrough at the library - explain the paper clip analogy/model.
Augusto used paper clips to describe the amino chains in Lorenzo's body. He used the smaller paper clips to describe
the "good" chains and the larger paper clips to describe the "bad" chains.
6. Dad was concerned when Lorenzo's friend came from Africa to live with the Adone's and care for Lorenzo. What
was Dad's primary concern?
Augusto was concerned that his friend could not speak English, also with where he would stay, and the with the racism
in the area that they lived.
7. Who was the first human subject to consume the oil and how was it dosed and administered through what portal
(ingested, injected, absorbed, inhaled, or other)?
Micheala's sister consumed the oil first as it was used as a salad dressing.
8. What is the role of money in this research product? Who paid for most of the early groundbreaking research?
Money was always a large part of being able to do the research. Towards the end of the movie, his parents mentioned
that they had to take out a second mortgage.
9. The critical mass theory suggests that multiple researchers conclusively find (or frequently stumble upon) an
answer to a scientific inquiry. Were the researchers on a single path to finding a cure for this disease?
For the most part, yes. The researchers were only focused on the diet of the individual in the beginning of the movie.
10. Consider ethics for a moment. Does this movie represent a appropriate ethical model for research. Defend your
answer.
I would not consider this movie as an ethical model for research. When the doctors could not do anything else, Lorenzo's
parents conducted research. They wanted to do everything they could to help their son, but I think they done it the
wrong way. But, in the end they did help more people other than their son.